鄭明剛,自然資源部第一海洋研究所副研究員,碩士生導師。2007年于中國海洋大學獲海洋生物學博士學位,2014年赴美國羅格斯大學公共衛(wèi)生與健康研究所進行生物化學與分子生物學領域的訪學研究。長期從事海洋微生物資源開發(fā)與生物技術研究,主持及參與國家重點研發(fā)計劃、國家自然科學基金、海洋公益項目等國家級及省部級科研項目10余項。主要研究方向包括:極端環(huán)境(深海熱液區(qū)、極地等)微生物資源的篩選與農業(yè)環(huán)境應用、近海新型有機污染物的分布特征及低溫微生物降解機制、兼具內切/外切活性的新型酶在基因編輯中的潛力探索。曾多次參與我國大洋與極地科學考察,具有豐富的海洋現場調查與研究經驗。
1. Xu, Mengxin, Zheng Minggang#, Ning Ke, Yang Ruixia, Wang Ling, Liu Aifeng,Qu Guangbo. Exploring factors influencing the spatial distribution and seasonal changes of BPA, TBBPA, and 20 analogs in China's marginal seas. JOURNAL OF HAZARDOUS MATERIALS. 2025. 487
2. Wang, Zechen, Ju, Peng, Chi, Jingtian, Han, Deman, Zheng Minggang*, Wang, Ling, Chen, Fengzao. Organic fluorescent dye rhodamine B-sensitized ZnIn2S4-gated organic photoelectrochemical transistors for bio-detection. SENSORS AND ACTUATORS B-CHEMICAL.2025. 427
3. Chen Hui, You Hairong, Cheng Jiaxin, Wang Shaohua, Chong Wei, Lou Xue, Kuang Shaoping, Liu Shuai, Zheng Minggang*, Liu Tao. Response of denitrifying anaerobic methane oxidation processes in freshwater and marine sediments to polyvinyl chloride microplastics. The Science of the total environment.2024. 955
4. Du Ming, Zheng Minggang#, Liu Aifeng, Wang Ling, Pan Xin, Liu Jun, Ran Xiangbin. Effects of emerging contaminants and heavy metals on variation in bacterial communities in estuarine sediments. SCIENCE OF THE TOTAL ENVIRONMENT 2022 832: 155118
5. Xu Hongyan, Zheng Minggang#, Wang Ling, Zhao Wucai, Hua Yi, Fang Lidan, Liu Aifeng, Zhao Zongshan. High throughput extraction strategy for simultaneous analysis of 19 tetrabromobisphenol A and halogenated carbazole analogs in seafood. FOOD CHEMISTRY 2021 350:129214
6. Zheng Minggang, Hu Shuya, Liu Xiaowen, Wang Wen, Yin Xiaocai, Zheng Li, Wang Ling, Lou Yinghua. Levels and distribution of synthetic musks in farmland soils from the Three Northeast Provinces of China. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2019 229:113101
7. Dong Xiaofeng, Zheng Minggang#, Qu Lingyun, Shi Lei, Wang Ling, Zhang Yu, Liu Xiaowen, Qiu Ying, Zhu Huihui. Sorption of Tonalide Musk Xylene Galaxolide and Musk Ketone by microplastics of polyethylene and polyvinyl chloride MARINE POLLUTION BULLETIN 2019 144: 129-133
8. Hu Shanmin, Zheng Minggang#, Mu Yingdi, Liu Aifeng, Jiang Yuqing, Li Ying, Ning Ke, Wang Ling. Occurrence of polyhalogenated carbazoles and the combined effects with heavy metals on variation in bacterial communities in estuarine sediments MARINE POLLUTION BULLETIN 2024,198:
9. Lei Jilin, Zheng Minggang#, Wang Ling, Yin Guobin, Lou Yinghua, Shi Lei. Complete genome sequence of Exiguobacterium mexicanum A-EM, isolated from seafloor hydrothermal vents in Atlantic Ocean.MARINE GENOMICS, 2021, 55:100801
10. Ma Liya, Wang Wen, Hao Chaozhi, Zheng Li, Wang Ling, Zheng Minggang*.Coexistence of endonuclease and exonuclease activities in a novel RecJ from Bacillus cereus, BIOTECHNOLOGY LETTERS, 2021, 43, 71349-1355
11. Wen Wang, Liya Ma,, Ling Wang, Li Zheng, Minggang Zheng*. RecJ from Bacillus halodurans possesses endonucleaseactivity at moderate temperature.FEBS Letters, 2020, 594, 2303–2310
授權專利
1.一種具有RecJ-piwi結構域的核酸酶及其在基因組隨機突變中的應用,國家發(fā)明專利,中國,ZL202211219015.8,授權公告年月2024.11.15
2.受DNAguide 引導的具有核酸內切酶活性的RecJ蛋白及其在基因編輯中的應用國家發(fā)明專利,中國,ZL20191 0509798.5 2021.8.27
3.受核苷酸片段引導具有特異核酸內切酶活性的PIWI蛋白,國家發(fā)明專利,中國 ZL201910061837.X,2019.01.22
4.一種富油海洋微藻及其應用,國家發(fā)明專利,中國,ZL2012 0154470.4 2013.6.26
獲獎與榮譽
1.2011年,所參加的課題“近海海洋微生物資源的標準化整理整合與共享”獲海洋局海洋創(chuàng)新成果獎獲獎二等獎。
2.2012年,所參加的課題“海洋微生物資源采集與國家海洋微生物資源共享平臺建設”獲海洋工程科學技術獎獲獎一等獎。